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      Athens Research:用專業(yè)與溫度,守護每一份科研期待

       更新時間:2025-06-20 點擊量:130

      Athens Research 2025年授權代理—上海起發(fā)

      自1986年以來,Athens Research & Technology Inc.一直致力于人類蛋白質(zhì)的純化及相應多克隆抗血清的開發(fā)。我們專注于提供高純度、高活性的人類蛋白質(zhì)產(chǎn)品,常規(guī)純化項目包括絲氨酸蛋白酶、蛋白酶抑制劑、中性粒細胞酶、載脂蛋白、脂蛋白、血小板蛋白、轉鐵蛋白、免疫球蛋白等。二十五年來,全球科研人員持續(xù)采購我們的研究試劑,這些產(chǎn)品在炎癥、冠心病、自身免疫疾病、癌癥、阿爾茨海默病等重大科學研究的文獻中屢被引用。

      我們還能從動物血清和組織中分離蛋白質(zhì)。

      國際診斷與制藥行業(yè)將我們的產(chǎn)品作為體外診斷試劑、免疫檢測試劑盒的核心組分,同時應用于細胞培養(yǎng)基(包括干細胞培養(yǎng)基)。雅典研究與技術公司的蛋白質(zhì)也被生物治療藥物研發(fā)人員用于概念驗證實驗。

      我們提供品質(zhì)可靠的產(chǎn)品與客戶服務——我們只銷售自主研發(fā)純化的產(chǎn)品。期待與您建立合作關系。

      若您需要定制化研究服務,將能提供項目所需的特殊試劑。

      熱門產(chǎn)品介紹

      1.Alpha 2 Antiplasmin

      Athens Research 2025年授權代理—上海起發(fā)

      貨號:16-16-012901

      分子量(MW):70,000  

      消光系數(shù):0.703  

      通過20 mM雙亞氨基三(羥甲基)甲烷(Bis-Tris)緩沖液(pH 6.4,含200 mM NaCl)凍干制得。  

      儲存條件:≤ -20°C  

      人血漿α2抗纖溶蛋白(凝血因子)  

      可有效抑制纖溶酶原激活劑誘導的纖維蛋白凝塊溶解。血漿中濃度約為70微克/毫升。α-抗纖溶蛋白缺乏癥是一種罕見的凝血功能障礙,會導致纖溶活性不受限。此類患者可在術前接受治療性α2抗纖溶蛋白(A2AP),以預防術后出血。  

      純度:≥95%(通過SDS-聚丙烯酰胺凝膠電泳檢測)  

      活性:≥5.0 單位/毫克  

      本品由經(jīng)FDA批準檢測顯示HBsAg、抗HCV、抗HBc陰性,且抗HIV 1/2陰性的血漿制備。  

      Athens Research & Technology產(chǎn)品為實驗室試劑,不可用于人體或作為藥物用途,僅限研究使用。  

      產(chǎn)品引用文獻:  

      Zimmerman, Thomas P., Valery Novokhatny, Shan Jiang, and James D. Colandene. "Reversibly inactivated acidified plasmin composition." U.S. Patent Application 13/761,684, filed February 7, 2013.

      Singh S, Houng A, Reed GL.

      Releasing the Brakes on the Fibrinolytic System in Pulmonary Emboli.

      Circulation. 2017 Mar 14;135(11):1011-1020. doi: 0.1161/CIRCULATIONAHA.116.024421. Epub 2016 Dec 27

      2.Myeloperoxidase Enzyme Immunoassay Kit

      Athens Research 2025年授權代理—上海起發(fā)

      貨號:K060-H1

      人髓過氧化物酶(MPO)酶聯(lián)免疫吸附試驗(EIA)試劑盒 特點:

      用途——檢測多種基質(zhì)中的人MPO  

      樣本類型——血清、無血小板肝素血漿、唾液、尿液或組織培養(yǎng)液  

      樣本量/盒——40份(重復檢測)  

      靈敏度——0.068納克/毫升  

      穩(wěn)定性——液體試劑于4°C下穩(wěn)定保存  

      快速出結果——2.5小時內(nèi)完成  

      髓過氧化物酶(MPO)是一種四聚體含血紅素蛋白,主要由中性粒細胞大量產(chǎn)生,在其中發(fā)揮重要的抗微生物作用。當粒細胞脫顆粒時,MPO會被釋放到細胞外空間。作為中性粒細胞“呼吸爆發(fā)"的一部分,它能通過過氧化氫(H?O?)和氯離子(Cl?)生成次氯酸(HOCl)。此外,MPO還能利用過氧化氫氧化酪氨酸生成酪氨酰自由基。次氯酸和酪氨酰自由基均具有細胞毒性,可有效殺滅細菌及其他病原體。遺傳性髓過氧化物酶缺乏癥會增加個體患免疫缺陷的風險。  

      研究表明,MPO水平升高與冠狀動脈疾病相關。2003年有研究提出,MPO可能作為胸痛患者心肌梗死的敏感預測指標。此后,大量文獻(已發(fā)表逾百篇)進一步證實了MPO檢測在心臟病患者中的臨床價值。2010年的補充研究進一步優(yōu)化了這一臨床應用:通過聯(lián)合檢測MPO和C反應蛋白(CRP),相較于單獨檢測CRP,可更精準地預測死亡風險。  

      參考文獻:  

      Zhang et al. (2001) Association between myeloperoxidase levels and risk of coronary artery disease; JAMA, 286 2135

      Brennan et al. (2003) Prognostic value of myeloperoxidase in patients with chest pain; New Engl. J. Med., 349 1595

      Heslop et al. (2010) Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography; J. Am. Coll. Of Cardiol. 55 1102

      Athens研究與技術公司(ART)與Arbor檢測公司合作,推出了目前MPO EIA試劑盒。Arbor檢測公司的創(chuàng)始團隊及頂尖科學家自1982年起便致力于研發(fā)高質(zhì)量檢測試劑盒。ART依托其30年在蛋白質(zhì)純化技術領域的經(jīng)驗,成功分離出高純度抗原;Arbor檢測團隊在此基礎上,通過抗體配對設計、精細優(yōu)化及嚴格的質(zhì)量控制(其標志性優(yōu)勢),最終開發(fā)出這款頂級酶聯(lián)免疫吸附試驗試劑盒。經(jīng)驗證,Athens研究與技術/Arbor檢測人MPO EIA試劑盒適用于血清、無血小板肝素血漿、唾液、尿液及組織培養(yǎng)液樣本,2.5小時內(nèi)即可完成檢測,靈敏度達0.068納克/毫升(注:原文此處可能存在筆誤,前文靈敏度為0.068 ng/mL,末段誤寫為0.68 ng/ml,翻譯保留原文數(shù)據(jù))。該試劑盒可通過任一合作公司購買(Arbor檢測貨號:K060-H1;Athens研究與技術貨號:K060-H1)。

      3.Apolipoprotein AI

      Athens Research 2025年授權代理—上海起發(fā)

      分子量(MW):28,000  

      消光系數(shù)(Extinction Coefficient):1.22  

      冷凍保存于10 mM NH?HCO?緩沖液(pH 7.4)中  

      儲存條件:≤-70°C  

      購買純化天然人載脂蛋白AI(ApoA1)(來源于人血漿)。可提供批量采購。  

      高密度脂蛋白(HDL)中75%的載脂蛋白A為Apo AI。Apo AI水平與冠心病風險呈負相關。此外,Apo AI被認為可激活卵磷脂膽固醇酰基轉移酶(LCAT)。正常血漿中,Apo AI水平范圍為90-130 mg/100 mL。  

      純度:通過SDS-PAGE檢測≥95%  

      本產(chǎn)品由經(jīng)FDA批準方法檢測為陰性的血漿制備(乙肝表面抗原[HBsAg]、丙肝抗體[anti-HCV]、乙肝核心抗體[anti-HBc]無反應;人類免疫缺陷病毒1型/2型抗體[anti-HIV 1 & 2]陰性)。  

      Athens Research & Technology產(chǎn)品為實驗室試劑,不可用于人體或任何藥物用途,僅限研究使用。  

      產(chǎn)品引用文獻:  Soffientini, Ugo, et al. "Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis." Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 1841.10 (2014): 1372-1382.

      Soffientini U, Dolan S, Graham A.

      Cytosolic lipid trafficking proteins STARD4 and STARD5 modulate hepatic neutral lipid metabolism: implications for diabetic dyslipidaemia and steatosis.

      Journal of Diabetes and Metabolism, Volume 6, Issue number 588. DOI: 10.4172/2155-6156.1000558.

      Winford, Sidney, Moriah Tobin, and Eitan Gross. "Surface-induced assembly of apolipoprotein AI: Implications for symmetry-driven non-cooperative clustering."Journal of Crystal Growth 343, no. 1 (2012): 38-44.

      Konno, Shunichi, Masami Tanio, Itsuko Ishii, Kazuhiko Machida, Fumiaki Matsumoto, Kaneshige Satoh, Masayuki Aso, and Yasushi Saito. "Ceiling culture-derived proliferative adipocytes are a possible delivery vehicle for enzyme replacement therapy in lecithin: cholesterol acyltransferase deficiency." Open Gene Therapy Journal 4 (2011): 1-10.

      Scharadin TM, et al.

      Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.

      PLOS One, 2017 Jun 6;12(6).

      Prathipati P, Zhu J, Dong X.

      Development of novel HDL-mimicking α-tocopherol-coated nanoparticles to encapsulate nerve growth factor and evaluation of biodistribution.

      Eur J Pharm Biopharm. 2016 Nov;108:126-135. doi: 10.1016/j.ejpb.2016.08.005. Epub 2016 Aug 12.

      核心優(yōu)勢

      技術深度與廣度兼?zhèn)洌焊采w抗體開發(fā)(多克隆/單克隆/重組抗體)、功能試劑盒(ELISA/Western Blot/流式檢測)、細胞培養(yǎng)(原代細胞/干細胞/類器官培養(yǎng)基)三大核心技術方向,可滿足從基礎研究到轉化醫(yī)學的全流程需求。

      嚴格的品控體系:所有產(chǎn)品均經(jīng)過“原料溯源-工藝驗證-性能測試-批次留樣"四步質(zhì)控,關鍵指標(如抗體親和力、試劑盒靈敏度)的批次間差異率≤5%,確保實驗結果可重復。

      定制化服務響應快:針對客戶的個性化需求(如新型抗原抗體開發(fā)、特殊物種細胞培養(yǎng)基優(yōu)化),提供“需求溝通-方案設計-樣品測試-量產(chǎn)交付"的全周期支持,平均定制周期較行業(yè)縮短30%。

      全球化的服務網(wǎng)絡:在美國、歐洲及亞太地區(qū)設立倉儲中心,支持48小時內(nèi)緊急訂單發(fā)貨;配備專業(yè)的技術支持團隊(含中文服務),為全球客戶提供7×12小時技術咨詢。

      目標客戶群

      高校/科研院所實驗室:為基礎醫(yī)學、生物學、藥學等領域的師生提供高性價比的研究工具,支持論文發(fā)表與課題申報。

      生物醫(yī)藥企業(yè)研發(fā)部:為新藥靶點驗證、藥效評價、臨床前研究提供定制化試劑(如疾病模型動物用抗體、細胞功能檢測試劑盒)。

      診斷試劑開發(fā)商:提供高特異性抗原/抗體原料,用于傳染病、腫瘤標志物等體外診斷試劑盒的開發(fā)。

      類器官/器官芯片研究團隊:定制化培養(yǎng)基與基質(zhì)膠產(chǎn)品,支持干細胞衍生類器官的高效培養(yǎng)與功能維持。

      您可能關心的問題及解答

      Q1:AR的抗體在跨物種檢測中表現(xiàn)如何?

      A:AR抗體開發(fā)時均經(jīng)過多物種同源性分析,優(yōu)先選擇保守表位設計抗原,確保在人、小鼠、大鼠等常見物種中具有良好的交叉反應性。若需特殊物種(如兔、猴)檢測,可提供定制化抗原表位設計服務。

      Q2:定制化產(chǎn)品的交付周期需要多久?

      A:常規(guī)定制(如抗體亞型轉換)約4-6周;復雜項目(如全新抗原開發(fā)+抗體篩選)約12-16周,具體時間根據(jù)需求復雜度評估后會與客戶確認。

      Q3:產(chǎn)品出現(xiàn)質(zhì)量問題如何解決?

      A:AR提供“30天無理由退換"服務(需保留完整包裝與使用記錄)。若因產(chǎn)品質(zhì)量問題導致實驗失敗,經(jīng)技術驗證后可免費補發(fā)或退款,并安排專人跟進解決。

      Q4:是否支持小批量采購?

      A:是的,AR提供毫克級抗體、微升級試劑盒及小規(guī)格培養(yǎng)基的采購選項,起訂量可根據(jù)客戶需求協(xié)商調(diào)整,降低中小實驗室的采購成本。

      Athens Research熱賣產(chǎn)品

      如對該品牌產(chǎn)品感興趣,歡迎咨詢:上海起發(fā)!

      貨號

      品名

      規(guī)格

      品牌

      16-16-090707-1M

      Immunoglobulin G1, Human Myeloma Plasma

      1mg

      Athens Research

      16-14-051200-100ug

      Elastase, Human Neutrophil

      100ug

      Athens Research

      16-16-090707-2M-1MG

      Immunoglobulin G2 Human Myeloma Plasma

      1mg

      Athens Research

      12-16-121601-1mg

      Lipoprotein (a), Human Plasma

      1mg

      Athens Research

      16-16-032001-LEL-1gram

      Transferrin (HOLO), Human Plasma, Tissue Culture Grade

      1gram

      Athens Research

      16-16-090705-100ug

      Immunoglobulin E, Human Plasma

      100ug

      Athens Research

      12-16-121601-100ug

      Lipoprotein (a), Human Plasma

      100ug

      Athens Research

      16-14-130000-1mg

      Myeloperoxidase, Human Neutrophil

      1mg

      Athens Research

      16-16-090701-1M-10mg

      Immunoglobulin A1, Human Myeloma Plasma

      10mg

      Athens Research

      16-16-161200-1mg

      Plasminogen, Human Plasma

      1mg

      Athens Research

      16-16-011609-5mg

      Alpha 1 Antitrypsin, Human Plasma

      5mg

      Athens Research

      16-16-120303-1mg

      Apolipoprotein CIII, Human Plasma

      1mg

      Athens Research

      16-16-161213-L-1mg

      Plasmin, Human Plasma (lyophilized)

      1mg

      Athens Research

      16-16-090701-1M-1mg

      Immunoglobulin A1, Human Myeloma Plasma

      1mg

      Athens Research

      16-16-090701-1M-5mg

      Immunoglobulin A1, Human Myeloma Plasma

      5mg

      Athens Research

      16-16-090707-1M-10mg

      Immunoglobulin G1, Human Myeloma Plasma

      10mg

      Athens Research

      12-16-120412-OX-1mg

      Lipoproteins, Oxidized, Low Density, Human Plasma

      1mg

      Athens Research

      16-14-012621-1mg

      Azurocidin, Human Neutrophil

      1mg

      Athens Research

      16-14-130000作廢

      Myeloperoxidase, Human Neutrophil

      100ug

      Athens Research

      16-16-090713-10mg

      Immunoglobulin M, Human Plasma

      10mg

      Athens Research

      16-16-090713-M-1MG

      Immunoglobulin M (IgM) Human Myeloma Plasma

      1mg

      Athens Research

      16-16-090713-Mfc5u-1mg

      Immunoglobulin M, Fc5mu, Human Plasma

      1mg

      Athens Research

      16-20-201319

      Thrombospondin, Human Platelet

      25ug

      Athens Research

      16-05-030112-P-1mg

      Calpain-1, Porcine Erythrocytes

      1 mg

      Athens Research

      16-14-030107-100ug

      Cathepsin G, Human Neutrophil

      100ug

      Athens Research

      16-14-051200-1mg

      Elastase, Human Neutrophil

      1mg

      Athens Research

      16-14-130000-100ug

      Myeloperoxidase, Human Neutrophil

      100ug

      Athens Research

      16-14-161820-25ug

      Proteinase 3 (PR3), Human Neutrophil

      25ug

      Athens Research

      16-16-030402-100ug

      C4b-Binding Protein, Human Plasma

      100ug

      Athens Research

      16-16-030402-1mg

      C4b-Binding Protein, Human Plasma

      1mg

      Athens Research

      16-16-081907-1mg

      Alpha 2 HS Glycoprotein, Human Plasma

      1mg

      Athens Research

      16-16-090701-10mg

      Immunoglobulin A1 (IgA1), Human Myeloma Plasma

      10mg

      Athens Research

      16-16-090701-2M-1mg

      Immunoglobulin A2, Human Plasma

      1mg

      Athens Research

      16-16-090707-1-1mg

      Immunoglobulin G1, Human Normal Plasma

      1mg

      Athens Research

      12-16-030825-1mg

      Chylomicrons, Human Plasma

      1mg

      Athens Research

      16-05-030112-P-100ug

      Calpain-1, Porcine Erythrocytes

      100 ug

      Athens Research

      16-12-030102-25ug

      Cathepsin B, Human Liver

      25ug

      Athens Research

      16-12-030102-50ug

      Cathepsin B, Human Liver

      50ug

      Athens Research

      16-13-090701-10mg

      Secretory IgA, Human Colostrum

      10mg

      Athens Research

      16-13-090701-5mg

      Secretory IgA, Human Colostrum

      5mg

      Athens Research

      16-14-012621-100ug

      Azurocidin, Human Neutrophil

      100ug

      Athens Research

      16-14-161820-100ug

      Proteinase 3, Human Neutrophil

      100ug

      Athens Research

      16-16-010700-10mg

      Alpha 1 Acid Glycoprotein (A1AGP), Human Plasma

      10mg

      Athens Research

      16-16-011609-1mg

      Alpha 1 Antitrypsin, Human Plasma

      1mg

      Athens Research

      16-16-012020-1mg

      Antithrombin III, Human Plasma

      1mg

      Athens Research

      16-16-012901-100UG

      Alpha 2 Antiplasmin, Human Plasma

      100ug

      Athens Research

      16-16-032001-1gram

      Transferrin (HOLO), Human Plasma

      1 gram

      Athens Research

      16-16-032001-CM-1mg

      Transferrin, Cynomolgus Monkey **

      1mg

      Athens Research

      16-16-032001-CM-5mg

      Transferrin, Cynomolgus Monkey

      5 mg

      Athens Research

      16-16-080116-1/1-1mg

      Haptoglobin, Phenotype 1-1, Human Plasma

      1mg

      Athens Research

      16-16-080116-2/2-1mg

      Haptoglobin, Phenotype 2-2, Human Plasma

      1mg

      Athens Research

      16-16-080116-5mg

      Haptoglobin, Human Plasma, Mixed Type

      5mg

      Athens Research

      16-16-090109-100ug

      Inter Alpha Inhibitor Proteins (IaIp), Human Plasma

      100ug

      Athens Research

      16-16-090707-1M-5mg

      Immunoglobulin G1, Human Myeloma Plasma

      5mg

      Athens Research

      16-16-090707-FC-1mg

      Immunoglobulin G, FC Fragment, Human Plasma

      1mg

      Athens Research

      16-16-090713-1mg

      Immunoglobulin M, Human Plasma

      1mg

      Athens Research

      16-16-110112-RAT-50ug

      Kallikrein, Rat Plasma

      50ug

      Athens Research

      16-16-120101-1mg

      Apolipoprotein AI, Human Plasma

      1mg

      Athens Research

      16-16-120500-1mg

      Apolipoprotein E, Human Plasma

      1mg

      Athens Research

      16-16-120500-50ug

      Apolipoprotein E, Human Plasma

      50ug

      Athens Research

      16-16-161801-1mg

      Prealbumin, Human Plasma (Transthyretin)

      1mg

      Athens Research

      01-05-030000-1ML

      Anti-Catalase Polyclonal Ab, Human Erthrocyte

      1ml

      Athens Research

      12-16-120412-5mg

      Lipoproteins, Low Density, Human Plasma

      5mg

      Athens Research

      12-16-221204-5mg

      Lipoproteins, Very Low Density, Human Plasma

      5mg

      Athens Research

      16-05-030000-1mg

      Catalase, Human Erythrocyte (50 KU per mg)

      1mg

      Athens Research

      16-12-030104-100ug

      Cathepsin D, Human Liver

      100ug

      Athens Research

      16-12-030104-25ug

      Cathepsin D, Human Liver

      25ug

      Athens Research

      16-12-030112-25ug

      Cathepsin L, Human Liver

      25ug

      Athens Research

      16-13-090701-1mg

      Secretory IgA, Human Colostrum

      1mg

      Athens Research

      16-13-A20103

      Apolactoferrin, Human Milk

      5mg

      Athens Research

      16-14-030107-50ug

      Cathepsin G, Human Neutrophil

      50ug

      Athens Research

      16-15-160518-100ug

      Eosinophil Peroxidase, Human Eosinophils

      100ug

      Athens Research

      16-16-011202-CM-10mg

      Albumin, Cynomolgus Monkey **

      10mg

      Athens Research

      16-16-012013-1mg

      Alpha 2 Macroglobulin, Human Plasma

      1mg

      Athens Research

      16-16-012400-1mg

      Alpha 1 Antichymotrypsin, Human Plasma

      1mg

      Athens Research

      16-16-012901-1MG

      Alpha 2 Antiplasmin, Human Plasma

      1mg

      Athens Research

      16-16-012901-500UG

      Alpha 2 Antiplasmin, Human Plasma

      500ug

      Athens Research

      16-16-030518-1mg

      Ceruloplasmin, Human Plasma

      1mg

      Athens Research

      16-16-080116-1mg

      Haptoglobin, Human Plasma, Mixed Type

      1mg

      Athens Research

      16-16-080513-LEL

      Hemopexin, Low Endotoxin Level, Human Plasma

      1mg

      Athens Research

      16-16-090109-1mg

      Inter Alpha Inhibitor Proteins (IaIp), Human Plasma

      1mg

      Athens Research

      16-16-090109-25ug

      Inter Alpha Inhibitor Proteins (IaIp), Human Plasma

      25ug

      Athens Research

      16-16-090701-1mg

      Immunoglobulin A, Human Plasma

      1mg

      Athens Research

      16-16-090705

      Immunoglobulin E, Human Plasma 1mg

      1mg

      Athens Research

      16-16-090705-M-Lambda-100ug

      Immunoglobulin E, Human Myeloma Plasma, Lambda

      100ug

      Athens Research

      16-16-090707

      人免疫球蛋白

      毫克

      Athens Research

      16-16-090707-2M-10mg

      Immunoglobulin G2, Human Myeloma Plasma

      10mg

      Athens Research

      16-16-090707-2M-5mg

      Immunoglobulin G2, Human Myeloma Plasma

      5mg

      Athens Research

      16-16-090707-4M-1mg

      Immunoglobulin G4, Human Myeloma Plasma

      1mg

      Athens Research

      16-16-090707-Fc-10mg

      Immunoglobulin G, Fc Fragment, Human Plasma

      10mg

      Athens Research

      16-16-090713-BULK

      Immunoglobulin M, Human Plasma

      1g

      Athens Research

      16-16-110112-50ug

      Kallikrein, Human Plasma (frozen)

      50ug

      Athens Research

      16-16-110112-CM

      Kallikrein, Cynomolgus Monkey Plasma

      50ug

      Athens Research

      16-16-110914-L-1mg

      Kininogen, Low Molecular Weight, Human Plasma

      1mg

      Athens Research

      16-16-120101-500ug

      Apolipoprotein AI, Human Plasma

      500ug

      Athens Research

      16-16-120101-LEL-1mg

      Apolipoprotein AI, Human Plasma, LEL

      1mg

      Athens Research

      16-16-120200-500ug

      Apolipoprotein B, Human Plasma

      500ug

      Athens Research

      16-16-180603-250ul

      Rheumatoid Factor (IgM), Human Plasma

      250ul

      Athens Research

      16-16-A32001-100mg

      APO Transferrin, Human Plasma

      100mg

      Athens Research

      16-16-A32001-1gram

      APO Transferrin, Human Plasma

      1gram

      Athens Research

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