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      C1酯酶抑制劑

       發布時間:2018/7/30 點擊量:1223

       

      Athens Research & Technology自1986年以來一直在凈化人類蛋白質和開發這些蛋白質的多克隆抗血清。我們專注于高純度,高活性的人類蛋白質。我們常規純化絲氨酸蛋白酶,蛋白酶抑制劑,中性粒細胞酶,載脂蛋白,脂蛋白,血小板蛋白,轉鐵蛋白,免疫球蛋白等。世界各地的研究人員已經從我們這里購買了這些研究試劑超過二十五年。您將看到我們的產品在炎癥,冠心病,自身免疫性疾病,癌癥,阿爾茨海默病等研究的主要科學出版物中被引用。

      我們還從動物血清和組織中分離蛋白質。

      我們的產品被診斷和制藥行業的先進者用作體外診斷和免疫測定試劑盒的組分,以及細胞培養基,包括支持干細胞的培養基。雅典研究和技術的蛋白質也被開發生物治療藥物的研究人員用于概念驗證研究。

       

      C1酯酶抑制劑,人血漿

      產品編號:

      16-16-031509

       

      MW:100,000 
      消光系數:0.4

      用含有250mMpotassium phosphate的20mM磷酸鉀(pH7.0)冷凍

      儲存:-70°C或更低

      購買純化的天然人C1酯酶抑制劑,人血漿。
      批量數量可用。

      單鏈糖蛋白,抑制C1,C1r,C1s,血漿激肽釋放酶,因子XIa。XIIa和纖溶酶。以每100毫升16-33毫克存在于血漿中。C1酯酶抑制劑缺乏是一種罕見的病癥,導致面部腫脹和腹部絞痛。通常情況是遺傳性的,盡管它也可能在C1EI無功能時發生。

      純度:通過SDS-PAGE> = 95%

      同義詞:補體C1酯酶抑制劑,酯酶抑制劑C-1

      通過FDA批準的測試,血漿制備顯示對HbsAG,抗-HCV,抗-HBc無反應,對抗-HIV 1和2呈陰性。

      雅典研究與技術產品是實驗室試劑,不得用于人體或用于任何藥物目的。僅供研究或進一步制造使用。

      產品引用:

      Salvesen,GS等人。1985. J. Biol?;瘜W。260,2432。

      Lee,Kyoung Geun,Haneulnari Lee,Jeong Mi Ha,Young Kyung Lee,Hee Jung Kang,Chung-Gyu Park和Sang Joon Kim。“增加的人腫瘤壞死因子-α水平在體外誘導豬內皮細胞的促凝血改變。”異種移植19,沒有。3(2012):186-195

      Kang,Hee Jung,Haneulnari Lee,Jeong-mi Ha,Jae-il Lee,Jun-Seop Shin,Ki-Yong Kim,Ji Yoon Park et al。“替代補體途徑在門靜脈內豬胰島異種移植后早期移植物丟失中的作用。” 移植(2014年)

      Kenninston JA,et al。高特異性活性位點阻斷抗體對血漿激肽釋放酶的抑制作用。J Biol Chem。2014年8月22日; 289(34):23596-608。doi:10.1074 / jbc.M114.569061。Epub 2014年6月26日。

      Zamolodchikov D,Renner T,Strickland S. 
      阿爾茨海默氏病肽β-淀粉樣蛋白通過激活凝血因子XII促進凝血酶的產生。
      J Thromb Haemost。2016年5月; 14(5):995-1007。doi:10.1111 / jth.13209。Epub 
      2016年2月29日。

       

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      6:我們還是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech;sysy,TriLink BioTechnologies,Inc;worthington-biochem,zyagen等幾十家國外公司授權代理。

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